Fis1, DLP1, and Pex11p coordinately regulate peroxisome …
May 1, 2007 · Taken together, these findings indicate that Fis1 plays important roles in peroxisome division and maintenance of peroxisome morphology in mammalian cells, possibly …
Fis1, DLP1, and Pex11p coordinately regulate peroxisome ... - scite
GDAP1-induced peroxisomal fission is dependent on the integrity of its hydrophobic domain 1, and on Drp1 and Mff, as is mitochondrial fission. Thus, GDAP1 regulates mitochondrial and …
PEX11 proteins attract Mff and human Fis1 to coordinate peroxisomal fission
Aug 15, 2012 · Based on peroxisomal targeting of PEX11γ mutated versions, we further elucidate how this protein interacts with the other PEX11 proteins and with members of the fission …
Molecular Complex Coordinating Peroxisome Morphogenesis in Mammalian ...
Jan 1, 2014 · Abstract Peroxisomal division comprises three stages: elongation, constriction, and fission. Potential candidates thus far studied for the factors involved in these stages include …
A role for Fis1 in both mitochondrial and peroxisomal fission in ...
Aug 17, 2005 · In this study, we have examined whether hFis1, a mammalian homologue of yeast Fis1, which has been shown to participate in mitochondrial fission by an interaction with …
PEX11β and FIS1 cooperate in peroxisome division ...
Jun 9, 2022 · Here, we reveal that PEX11β can promote peroxisome division in the absence of MFF in a DRP1- and FIS1-dependent manner. We also demonstrate that MFF permits …
Peroxisome homeostasis: Mechanisms of division and selective ...
May 1, 2016 · Taken together, these findings suggest that in mammalian cells Fis1 contributes less to the peroxisomal fission mediated by the ternary complex consisting of Pex11β, Mff, and …
Based on peroxisomal targeting of PEX11γ mutated versions, we further elucidate how this protein interacts with the other PEX11 proteins and with members of the fission machinery.
PEX11β and FIS1 cooperate in peroxisome division independently …
Jul 8, 2022 · To probe the role of FIS1 in MFF-independent, PEX11β-dependent peroxisome fission, we overexpressed PEX11β in Mff and Fis1 knockout (KO) mouse embryonic …
PEX11 proteins attract Mff and human Fis1 to coordinate peroxisomal …
Fission of membrane-bound organelles requires membrane remodeling processes to enable and facilitate the assembly of the scission machinery. Proteins of the PEX11 family were shown to …
PEX11 proteins attract Mff and human Fis1 to coordinate peroxisomal …
May 17, 2012 · Fission of membrane-bound organelles requires membrane remodeling processes to enable and facilitate the assembly of the scission machinery. Proteins of the PEX11 family …
A role for Fis1 in both mitochondrial and peroxisomal fission ...
Nov 1, 2019 · In this study, we have examined whether hFis1, a mammalian homologue of yeast Fis1, which has been shown to participate in mitochondrial fission by an interaction with …