Pyogenic granuloma of the skin presents as a painless red fleshy nodule, typically 5-10mm in diameter, that grows rapidly over a few weeks. The surface is initially smooth but can ulcerate, become crusty, or verrucous.

What is a pyogenic granuloma? Pyogenic granuloma is an acquired benign proliferation of capillary blood vessels of the skin and oral cavity. The name is a misnomer as it is a form of lobular capillary haemangioma, not due to infection. Pyogenic granuloma has many synonyms including granuloma gravidarum or pregnancy tumour when occurring in ...

Reactive haemangioma or pyogenic granuloma has a distinct keratinised border or collarette. Vascular structures are usually present but there is no clear lacunar pattern. White linear 'rail lines' are often featured. It is not always possible to distinguish reactive haemangioma from amelanotic melanoma.

A granuloma is a chronic inflammatory pattern characterised by the localised aggregation of histiocytes with or without other inflammatory cells (eg plasma cells, eosinophils, neutrophils), with or without necrosis, with or without vasculitis, with …

Pyogenic granuloma. Pyogenic granuloma is one form of lobular capillary haemangioma. There is a characteristic collarette of skin around a juicy or friable red nodule that bleeds easily. Pyogenic granuloma sometimes follows minor trauma. Staphylococcus aureus is often isolated. Pyogenic granuloma is particularly common on lips and fingers, and ...

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Clinically it can be difficult to distinguish from other common lumps in the mouth such as pyogenic granuloma, oral irritation fibroma, giant cell fibroma or peripheral giant cell granuloma. How is peripheral ossifying fibroma diagnosed?

Pyogenic granuloma; Actinic keratoses (most are better frozen) In situ squamous cell carcinoma (Bowen disease) Keratoacanthoma (if there is no clinical doubt about the diagnosis) Superficial basal cell carcinoma (in experienced hands) Well demarcated and small nodular or cystic basal cell carcinoma; Lesions suitable for shave/curettage

The differential diagnosis of foreign body granulomas includes other forms of granuloma and other reactions to foreign bodies (for example in-growing hairs can cause pseudofolliculitis, especially in the beard area). The differential diagnoses include: Cutaneous sarcoidosis; Granuloma annulare; Pyogenic granuloma; Granuloma faciale

Histologically, there may be some similarities with lobular capillary haemangioma (pyogenic granuloma). However, capillaries here are arranged in a more prominent lobular formation, less dilated and often display endothelial cell cytological atypia and numerous mitoses not seen in cherry angioma.