Gout = Negatively birefringent, needle-shaped monosodium urate crystals; Pseudogout = Positively birefringent, rhomboid-shaped, calcium pyrophosphate crystals; Serum uric acid …

Presentation of gout (presents in four ways): Acute urate synovitis (acute attack of gout – what is mainly covered here). Classically, acute gout affects the first MTP (podagra): initial …

Oct 21, 2023 · Under polarized light microscopy, CPPD crystals appear blue, a property called positive birefringence. This distinguishes them from the negatively birefringent crystals of gout. …

Sep 14, 2022 · Gout is a metabolic disorder that affects joints, bones, skin and soft tissues. It is associated with hyperuricemia, which causes saturation of monosodium urate and eventual …

Negatively birefringent urate crystals are seen on polarizing examination in 85% of specimens. Microscopic analysis in pseudogout shows calcium pyrophosphate (CPP) crystals, which …

Mar 17, 2025 · Explore the microscopic characteristics of gout crystals, their birefringence patterns, and key techniques for accurate identification and differentiation. Gout is a painful …

Nov 8, 2023 · Gout is a form of inflammatory arthritis caused by intraarticular monosodium urate crystal deposition that typically presents with recurrent acute exacerbation of joint swelling and …

Nov 3, 2021 · Gout and pseudogout can be differentiated by examination of the fluid aspirate contents of a joint viewed under polarised red light: Urate crystals – are negatively birefringent …

Feb 12, 2025 · crystal analysis will demonstrate weakly positive birefringent rhomboid crystals under polarized light

Positively birefringent rhomboidal crystals of (Calcium pyrophosphate dihydrate) 60s to 70s, (F>M) Most common cause of acute arthropathy in the elderly; Classically knees; …