A fact sheet about the BRCA1 and BRCA2 genes, what to do if a person tests positive for alterations in one of these genes, and consequences of genetic testing.

Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks associated with …

Hoja informativa sobre los genes BRCA1 y BRCA2, qué hacer si la prueba de una persona indica que tiene cambios en uno de estos genes y las consecuencias de las pruebas genéticas.

Gen que da origen a una proteína que repara el ADN dañado. Las mutaciones (cambios) en el gen BRCA1 aumentan mucho el riesgo de presentar cáncer de mama y cáncer de ovario.

A gene that makes a protein that repairs damaged DNA. Mutations (changes) in the BRCA1 gene significantly increase the risk of developing breast and ovarian cancer.

NCI-funded research helped identify inherited BRCA1 and BRCA2 genetic mutations and their connection to breast and ovarian cancer. From this research, a screening test was also developed to …

A fact sheet about genetic testing for inherited cancer risk. Includes who should consider testing, and how to understand test results.

Dec 2, 2025 · Learn about causes of breast cancer and factors that increase risk, such as your health history, genetics, and certain behaviors.

Apr 15, 2024 · For women with inherited harmful changes in BRCA genes, MRI surveillance and salpingo-oophorectomy can modestly reduce their risk of dying from breast and ovarian cancer, …

BRCA1 is a nuclear phosphoprotein that functions as a tumor suppressor. BRCA1 combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit …