Two separate incidents on I-81 northbound led to significant traffic backups Wednesday evening, according to PennDOT.

A tractor-trailer hauling Target merchandise crashed into a bridge over I-81 in Cumberland County Friday morning, spilling ...

Part of Interstate 81 is closed Friday morning in Cumberland County after a tractor-trailer carrying Target products hit an ...

PennDOT said a tractor-trailer hit the bridge overpass for Stoughstown Road over I-81 north around 8:30 a.m. Friday.

A huge tornado was seen twisting over a field south of Gary, South Dakota, on June 28, as severe storms swept the area. The ...

Emergency pothole repairs will close the right lane of Interstate 81 southbound near Staunton through tomorrow morning. The ...

Gov. Glenn Youngkin will cut the ribbon this morning on the new Buc-ee’s travel center on Interstate 81 in Rockingham County, ...

The incident happened just after 5 a.m. on Interstate 70 near Interstate 81, according to myfox8. Maryland State Police (MSP) ...

SYRACUSE, N.Y. — Interstate 81 northbound will be reduced to one lane between Exit 18 (Adams St/Harrison St) and the ...

A West Virginia man is in custody in connection with a road-rage incident reported on Interstate 81 last week.

On Tuesday, July 1st at 6:35pm, the Cortlandville Fire Department was alerted for a reported vehicle fire at the 47-mile ...

Delays are easing on Interstate 81 after a crash that happened shortly after noon on Thursday. Video above: Headlines from ...