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Diageo, the maker of Guinness stout and Smirnoff vodka, announced Wednesday that its chief executive Debra Crew had stepped down with immediate effect.

Diageo CEO Debra Crew resigned as the maker of brands including Smirnoff vodka and Guinness beer struggles with weak sales.

Debra Crew's departure after two years comes as the beer and spirits giant has battled tariffs and a drop in alcohol consumption.