UCLA Health researchers have identified four distinct pathways that lead to Alzheimer's disease by analyzing electronic health records, offering new insights into how the condition develops over ...

Background: Recently, reports of influenza-associated encephalopathy have increased worldwide. Given the high mortality and morbidity rates attributable to this severe neurologic complication of ...

Sepsis-associated CVD mortality increased in the United States after the start of the COVID-19 pandemic, with the highest rates observed in older adults and Black patients.

Neurocognitive disorders related to postoperative sepsis, which share pathophysiological similarities with sepsis-associated encephalopathy, involve neuroinflammation, blood–brain barrier disruption, ...

Scientists have developed a cortical organoid model for UBA5-associated encephalopathy, revealing a new way to possibly address developmental defects.

Treatment for UBA5 -associated encephalopathy is currently limited to addressing the symptoms and managing the severe deficiencies in muscle tone and physical ability caused by the disorder.

Both sepsis and bacteremia involve bacteria in the bloodstream. Bacteremia generally is not a serious condition, but sepsis can be life-threatening.

A ratio of serum aspartate aminotransferase to alanine aminotransferase levels serves as a strong prognostic tool to stratify the 30-day mortality risk in patients with sepsis-associated liver injury.

This research could be a game-changer.” Abstract Lipopolysaccharide (LPS) is the primary pathogenic factor in Gram-negative sepsis. While the presence of LPS in the bloodstream during infection is ...

Sepsis patients could get the right treatment faster, based on their genes Date: June 18, 2024 Source: Wellcome Trust Sanger Institute Summary: New study into the molecular pathways involved in ...

Sepsis induces neuroinflammation, BBB disruption, cerebral hypoxia, neuronal mitochondrial dysfunction, and cell death causing sepsis-associated encephalopathy (SAE). These pathological consequences ...