On the basis of the overall histology, the cases were placed in one of the following categories: normal/near normal, ischemia-like, inflammatory bowel disease-like, graft- vs -host disease-like ...

Samples of normal mucosa were taken as far away as possible from the tumour site and were morphologically normal in sections used to evaluate the status of that margin in routine histology.

When these switches were applied to colon cancer cells, the cancer cells reverted to a normal-like state, a result confirmed through molecular and cellular experiments as well as animal studies.

Adenocarcinoma commonly affects the lungs and the colon. Each of the organs when affected by adenocarcinoma show a different histopathology.