It is still unclear whether presence of macromolecules in the highly protein‐rich mitochondrial matrix fluid affects solute diffusion and biochemical reactions remains unclear. This study identifies ...

This review article provides a comprehensive overview of stress granules (SGs) —membraneless organelles formed in response to cellular stress—and their interactions with other organelles. It ...

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such ...

Not only do mitochondria serve as the engine of the cell – they also act as watchtowers for the immune system.

Chimera approach overcomes mitochondrial barrier to alter protein production in living cells by Universitätsmedizin Göttingen ...

Mitochondria, after all, perform a variety of crucial functions in the human body. Beyond powering cells, they can affect gene expression, help certain enzymes function, and modulate cell death ...

Membraneless liquid droplets called stress granules can concentrate TDP-43. Oxidation of the protein in these blobs triggers a liquid-to-solid transition. Disulfide bonds and structural changes in the ...

SP11 molecule reverses mitochondrial fragmentation, restoring energy production in stressed cells by SLAC National Accelerator Laboratory ...

Amazingly, my co-workers and I have discovered that mitochondria are themselves social beings. At least, they foreshadow sociality. Like the bacterium they descended from, they have a life cycle ...

The number of mitochondrial DNA copies may drop as MS progresses, suggesting a possible biomarker for disease progression, a study found.

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

“The mitochondrial pyruvate carrier (MPC) is responsible for transporting pyruvate, produced from sugars by glycolysis in the cytosol, into the mitochondrial matrix,” the authors explained.