Rearrangement of immunoglobulin heavy-chain variable (VH) gene segments has been suggested to be regulated by interleukin 7 signaling in pro–B cells. However, the genetic evidence for this ...

To identify immunoglobulin variable heavy chain (VH) gene usages in Korean ankylosing spondylitis (AS) patients, expression level of VH2 genes from peripheral blood mononuclear cells (PBMCs) of 8 ...

The course of chronic lymphocytic leukemia (CLL) is variable. In aggressive disease, the CLL cells usually express an unmutated immunoglobulin heavy-chain variable-region gene (IgV H) and the 70 ...

Use of immunoglobulin heavy chain primer pools to assess minimal residual disease/persistent disease ... Presence of residual chromosomal aberrations and/or clonal immunoglobulin gene rearrangements ...

Researchers isolated SARS-CoV-2 spike protein-targeted mAbs from convalescent healthcare workers, emphasizing the IGHV1-69 gene, the gene with the greatest structural and allelic variation.