Our findings indicate that duration of attenuated virus vaccine burden is a determinant of humoral and cellular immunity and also suggest that vaccines that elicit both arms of the adaptive immune ...

AdV vector-based vaccines are capable of eliciting both humoral and cell-mediated immune (CMI) responses (2, 3) by stimulating innate immunity through both Toll-like receptor (TLR)-mediated and ...

In this eBook, we review biomarker discovery, emphasizing immunoprofiling with autoantibody signatures, that once deconvoluted with machine learning, can provide insights into disease progression ...

Researchers longitudinally evaluated humoral immune responses to the second and third doses of COVID-19 mRNA vaccines among individuals with and without prior history of SARS-CoV-2 infections.

Specific Anti-SARS-CoV-2 Humoral and Cellular Immune Responses After Booster Dose of BNT162b2 Pfizer-BioNTech mRNA-Based Vaccine: Integrated Study of Adaptive Immune System Components ...

In this prospective longitudinal study, we found a significant waning of humoral responses within 6 months after receipt of the second dose of BNT162b2 vaccine in a large cohort of 4868 participants.

While humoral immunity attacks invaders circulating outside cells largely via the generation of antibodies, the other adaptive immune system component, cellular immunity, targets invaders inside ...

The study, published in the journal Science Immunology, revealed that some SARS-CoV-2 variants could partially escape humoral immunity induced by infection or vaccination.

Maintenance of long-term antibody responses is critical for protective immunity against many pathogens. However, the duration of humoral immunity and the role played by memory B cells remain poorly ...