Q2: What is the significance of the focus on heavy rare earths given U.S. supply chain vulnerabilities? A2: The restrictions apply to seven medium and heavy rare earths: samarium, gadolinium, terbium, ...

In preclinical work recently published in Nature Communications, Fred Hutch Cancer Center scientists used a genetic “chain reaction” to transform herpes simplex virus DNA during an HSV infection. The ...

Dynein-2 is a large multiprotein complex that powers retrograde intraflagellar transport (IFT) of cargoes within cilia/flagella, but the molecular mechanism underlying this function is still emerging.

The specificity amino acid replacements were found to be identical in the IgM and IgG heavy chains whether the two antibodies were isolated from and individual animal of a1 or a3 allotype. These ...

The paper explained Problem Mutations in the MYH3 gene encoding the myosin heavy chain‐embryonic (MyHC‐embryonic) protein lead to several human congenital musculoskeletal diseases such as ...

Health outcomes modelling of RNA-based versus DNA-based detection of driver gene rearrangements in non-small cell lung cancer.

Analytical techniques and computational models reveal novel post-translational modifications on β-myosin heavy chain in the human hearts and highlight their potential as therapeutic targets.

Both groups also retained some other essential processes, such as segregated and sequential rearrangement of heavy and light chain loci, preferential rearrangement of light chain kappa before lambda, ...

Moreover, we observed that LD content was tightly connected with the iron metabolism and in particular with the presence of the ferritin heavy chain (FTH1). In fact, breast and lung cancer cells ...

Extensive diversity has been identified in the human heavy chain immunoglobulin locus, including allelic variation, gene duplication, and insertion/deletion events. Several genes have been suggested ...

Inherited mutations in DNA-repair genes such as BRCA2 are associated with increased risks of lethal prostate cancer. Although the prevalence of germline mutations in DNA-repair genes among men with ...

Background—Recent genome-wide association studies have demonstrated an association between MYH6, the gene encoding α-myosin heavy chain (α-MHC), and sinus node function in the general population.