Rearrangement of immunoglobulin heavy-chain variable (VH) gene segments has been suggested to be regulated by interleukin 7 signaling in pro–B cells. However, the genetic evidence for this ...

The only immunoglobulin heavy-chain classes known so far in teleosts have been μ and δ. We identify here a previously unknown class, immunoglobulin ζ, expressed in zebrafish and other teleosts.

Weiss, A, McDonough, D, Wertman, B, et al. Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved. Proc Natl Acad Sci U S A 1999;96:2958-2963.

TEL gene rearrangements due to the 12;21 chromosomal translocation are the most common molecular genetic abnormality in childhood acute lymphoblastic leukemia (ALL), occurring in approximately 25% of ...

Reduction in antibody gene rearrangement in B cells related to type 1 diabetes, lupus Implications for new tests and more personalized treatments for autoimmune diseases Peer-Reviewed Publication ...

A genetic locus for mutations associated with dilated cardiomyopathy was identified at chromosome 14q11.2–13 (maximal lod score, 5.11; θ=0), where the gene for cardiac β-myosin heavy chain is ...