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Want to catch a criminal? Show a mugshot on the news. Want to stop HIV infections? Get the immune system to recognize and attack the virus’s tell-tale structure. That’s part of the basic approach ...
The new Science Express study reveals the structure of the CCR5 cell surface receptor, which most strains of HIV use to enter human immune cells. This image shows CCR5 side-by-side with alternate ...
This week, a new paper described how researchers pieced together the entire molecular structure of the protein shell of the HIV virus using GPU-based simulations. This remarkable achievement not ...
A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.
Antiviral therapy could be improved with newly uncovered atomic-level details of the structure of HIV machinery, report researchers. Salk Institute scientists have solved the atomic structure of a ...
Scientists have provided the first-ever glimpse of the structure of a key protein -- gp120 -- found on the surface of a specific subgroup of the human immunodeficiency virus, HIV-1. In addition ...
Here, we present the cryo-EM structure, at subnanometer resolution (∼6 Å at 0.143 FSC), of the 'closed', prefusion state of trimeric HIV-1 Env complexed to the broadly neutralizing antibody VRC03.
A new technique using electron tomography and subtomogram averaging at Diamond’s electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host ...
Maraviroc thus appears to work against HIV indirectly: not by physically blocking the virus, but by locking the receptor structure into an HIV-insensitive conformation. "Structural details can ...
(Nanowerk News) In a long-awaited finding, a team of Chinese and US scientists has determined the high-resolution atomic structure of a cell-surface receptor that most strains of HIV use to get into ...