While hydroxychloroquine (HCQ) helps reduce disease flares in lupus, its effect on renal function in patients with lupus ...

The Company will also present preclinical data in an animal model of immune-mediated FSGS showing that optimized dual endothelin and angiotensin blockade with FILSPARI helps protect the integrity of ...

I'm also a podocyte protector, if you will. If everyone goes back to their days of the anatomy of glomeruli, the podocyte is an important cell for maintaining the glomerular filtration barrier.

The absence of EMCN likely disrupts the glomerular filtration barrier by compromising endothelial glycocalyx and tight junction integrity, contributing to increased immune cell infiltration and ...

About 90% of people living with a condition that is one of the leading causes of death in the United States are unaware that they have it.

Insights into the role of ADGRF5 aids the understanding of glomerular disorders and significantly contributes to the advancement of future research." Unlocking the novel functions of the ADGRF5 ...

Unlocking the novel functions of the ADGRF5 receptor holds promise for pioneering therapeutic breakthroughs in treating glomerular filtration barrier dysfunctions, notably proteinuria.

Unlocking the novel functions of the ADGRF5 receptor holds promise for pioneering therapeutic breakthroughs in treating glomerular filtration barrier dysfunctions, notably proteinuria.

Automatic segmentation of the three substructures of glomerular filtration barrier (GFB) in transmission electron microscopy (TEM) images holds immense potential for aiding pathologists in renal ...

These cells play an important role in maintaining the integrity of the glomerular filtration barrier in conjunction with the adjacent basement membrane and endothelial cell layers within the ...

Findings of minimal change disease in adults and children with autoantibodies targeting nephrin supports prior research demonstrated in animal models.“Failure of the glomerular filtration ...

Kidney disease is characterized by loss of glomerular function with clinical manifestation of proteinuria. Identifying the cellular and molecular changes that lead to loss of protein in the urine is ...