Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...

In a breakthrough study, scientists found that silencing a single overactive enzyme in the brain reversed early damage caused ...

Nutrition scientists have been working to understand the relationship between type 2 diabetes and genes that express a ...

By combining artificial intelligence with automated robotics and synthetic biology, researchers at the University of Illinois ...

By combining artificial intelligence with automated robotics and synthetic biology, researchers at the University of Illinois ...

Mutations in EGLN1, the gene encoding for hypoxia-inducible factor (HIF) prolyl-4-hydroxylase 2 (PHD2), cause erythrocytosis and in rare cases the development of neuroendocrine tumors. In the presence ...

From cancer to infectious diseases to neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, there ...

AMSBIO has introduced a new series of Deubiquitinating (DUB) enzyme assay kits that streamline the analysis of DUB activity in both purified systems and cell-based models. Supplied in a convenient ...

Designed to quickly measure deubiquitinase activity or inhibitor screening in purified enzyme systems and cell-based models - these new assay kits come optimized for both kinetic and endpoint analysis ...

AMSBIO (Oxford, UK) has launched a new range of deubiquitinating (DUB) enzyme assay kits supplied in a convenient and easy-to-use 96-well assay format. With minimal setup required and no need for ...

Reviewer #1 (Public review): Summary: Mancl et al. present cryo-EM structures of the Insulin Degrading Enzyme (IDE) dimer and characterize its conformational dynamics by integrating structures with ...

In vitro, purified prorenin can be induced to exhibit reversible enzymatic activity by prolonged exposure to acid pH or cold storage. 2930 Thus, 1 possible explanation for the prorenin activity seen ...