Keywords: Ebola, small molecule antiviral drugs, drug discovery, SuFEx, direct-to-biology Citation: Dada L, Nagai E, Agrawal S, Wirchnianski AS, Wilson IA, Chandran K and Kitamura S (2025) ...

Discovered in 1976, Ebola is rare, deadly and has multiple variations. There is a vaccine for the Zaire type, now trials for another are underway.

Discovered in 1976, Ebola is rare, deadly and has multiple variants. There is a vaccine for the Zaire type. Now, trials for another strain are underway.

Results The Ebola virus VP40 matrix undergoes disassembly in endosomal compartments To shed light on endosomal uncoating of EBOV virions at molecular resolution, we infected Huh7 cells cultured on ...

Pseudotyped viruses As described in McWilliams IL et al., 24 we obtained the VSV-G-deleted Vesicular Stomatitis Virus containing the Zaire (Mayinga) Ebolavirus glycoprotein (VSV-EBOV) from BEI ...

A new study suggests the antiviral drug obeldesivir may be effective in curing Ebola Sudan infections, for which there are currently no approved vaccines or treatments.

To identify cellular proteins that interact with VP24, we cloned the gene encoding EGFP either 5′ or 3′ of a gene encoding codon-optimized VP24 from a virus similar to the Zaire EBOV, Mayinga Strain ...