Individuals with cystic fibrosis or CFTR gene variants have a 3-fold higher risk of developing pancreatic cancer after 50 years of age.

Transabdominal ultrasound shows potential as an alternative and cost-effective method for monitoring selected patients with cystic pancreatic lesions.

Growing up, it wasn’t my cystic fibrosis that fueled my anxiety — it was the checklist of mental tasks I believed would prevent disaster. It wasn’t until adulthood that I learned this behavior is ...

Chronic lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), are major leading causes of death worldwide and are generally associated with poor ...

Objective Extracellular matrix protein 1 (ECM1) serves as a gatekeeper of hepatic fibrosis by maintaining transforming growth factor-β1 (TGF-β1) in its latent form. ECM1 knockout (KO) causes latent (L ...

Zhao H, Long L, Yan Y, Wang Z, Zhao H, Li L. Acute pulmonary interstitial fibrosis caused by anti-GBM disease combined with ANCA-associated vasculitis-the role of combined cardiopulmonary ultrasound ...

Cystic fibrosis transmembrane conductance regulator (CFTR), a Cl−-ion channel, assembles into dynamic macromolecular complexes. Understanding how these complexes regulate the intracellular ...

A significantly larger proportion of individuals who received antifibrotic and pulmonary vasodilator therapy had severe pulmonary hypertension compared with those prescribed antifibrotic therapy alone ...

Background Clinical trials in cystic fibrosis (CF) have been hindered by the paucity of well characterised and clinically relevant outcome measures. Aim To evaluate a range of conventional and novel ...

With the improving survival of patients with cystic fibrosis (CF), the clinical spectrum of this complex multisystem disease continues to evolve. One of the most important clinical events for patients ...

Sionna Therapeutics, Inc. has announced the presentation of promising preclinical data at the 48th European Cystic Fibrosis Conference in Milan, showing that its nucleotide-binding domain 1 (NBD1 ...

RALEIGH, N.C. — When he was about 14, Pete Proimos learned a soul-crushing statistic about the cystic fibrosis he’d endured since birth: Patients back then didn’t live much past high school.