Tumor cell invasion into the basement membrane is an important step in the multistep process of cancer metastasis (Liotta, 1986).Various in vitro assay systems have been developed for the ...

KGN cell invasion is compared to LP9 mesothelial cells. Results are shown as mean ± SD cell index from triplicate wells at 24 hours (B) and over an entire two-day assay period (C). Figures ...

BellBrook Labs announced the publication of studies on an enabling new approach for studying tumor cell invasion entitled “An Automated High-Content Assay for Tumor Cell Migration through ...

In vitro invasion assay. Cancer cell invasiveness was determined using transwell chamber (Costar, Cambridge, MA, USA) coated with 0.3 μg/μl matrigel (Collaborative Research Inc., ...

More information: James R. W. Conway et al, Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells, Nature Cell Biology (2025). DOI: 10.1038/s41556-025-01663-4 ...

This tool uncovered new therapeutic possibilities for limiting breast cancer spread and increased understanding of cancer cell invasion, which could extend to other solid tumors. When breast cancer ...

The implementation of cell-based assays can improve the process of drug discovery and development by providing important biological information about drug action mechanisms, off-target effects ...

DURHAM, N.C. -- What makes some cancer cells stay put while others break loose and spread through the body? A new study of C. elegans worms may hold some clues. Researchers at Duke University have put ...

CHICAGO — A 14-gene molecular assay could help predict which patients with early-stage non-small cell lung cancer will benefit from adjuvant chemotherapy, according to results of the AIM HIGH ...

This webinar will be hosted live and available on-demand. Thursday, April 3rd, 2025 11:00 AM - 12:30 PM ET. In the immuno-oncology field, scientists discover, test, and validate novel ...