Metastasis is a serious disease caused by primary tumor cell dissemination to different organs. Although, invasion of primary tumor cell is the initial step required in tumor metastasis, migration is ...

Cancer cells possess a broad spectrum of invasion mechanisms. Quantitative analysis of cancer cell invasion process under tested condition is important to precisely study the cellular invasion ...

HealthDay News — A rapid nanosensor assay that measures serum protease cleavage of a target-probe nanosensor can identify pancreatic ductal adenocarcinoma (PDAC) samples with high specificity ...

Abstract The intricate interplay between actomyosin contractility and extracellular matrix (ECM) strain stiffening is pivotal in cancer invasion. Despite the admitted impact of such feedback, current ...

The implementation of cell-based assays can improve the process of drug discovery and development by providing important biological information about drug action mechanisms, off-target effects ...

The cell migration and invasion assay market is estimated to be worth $1.3 billion. Cell invasion assays empower researchers to understand the vital process in various biological contexts that can be ...

Taken together, our findings suggest that the mechanisms underlying nerve recruitment/outgrowth and perineural invasion may be partly decoupled. To further test this hypothesis, we are performing ...

Figure 1. Thy-1 induces migration and invasion of MDA-MB-231 cells in a β 3 Integrin-dependent manner. (A) Wound-healing assay in non-stimulated (NS), MDA-MB-231 cells, or cells treated with ...

Transwell cell migration/invasion and scratch wound assays were used to investigate the OSCC cell migration and invasion in vitro. Kaplan-Meier survival analysis was used to investigate the ...

Additional information on plasmid constructs and lentivirus production, cell culture and generation of stable cell lines, spheroid formation and invasion assay, drug treatments, blocking antibodies, ...