These proteins can have too many conformations for researchers to keep track of, says Kejia Wu, a postdoctoral researcher ...

An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin has ...

Many proteins are capable of spontaneously rearranging themselves within cells to form molecular condensates—membraneless ...

David Baker’s lab has successfully designed binders to disordered proteins, expanding therapeutic access to over 50% of the human proteome.

Scientists David Baker's UW lab are using generative AI to target 'undruggable' proteins for creating new drugs and ...

A research team with Professor Neha Kamat used synthetic liposomes and bacterial extracts to generate immune responses ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Computational protein design (CPD) offers transformative potential for bioengineering, but current deep CPD models, focused on universal domains, struggle with function-specific designs. This work ...

Protein design has emerged as a viable computational technique for providing alternative therapeutic strategies. Protein design technologies enable the creation of a diverse range of novel proteins ...

The use of molecular modifiers as crystal growth inhibitors is a common approach in crystal engineering, yet relatively few studies are devoted to designing these species as accelerants of crystal ...