Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

PD-1 inhibitor combined with ablation in liver metastasis: A retrospective, multicenter study. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Hdy-7 directly binds to TrxR1/2, triggering ROS accumulation and p53 activation. Activated p53 negatively regulates mTORC1 signaling, which is one of the major kinases responsible for the ...

Autophagy is a natural, conserved process where cells degrade and recycle their own components, including damaged proteins and organelles. This targeted removal is orchestrated by cargo receptors, ...

Invisible plastic fragments from common tableware are turning up in semen; now, researchers reveal how nanoscale particles may quietly sabotage male reproductive biology through cellular stress and ...

A study has identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain. A study led by researchers from the University of ...

Combining proteasome inhibitors with autophagy inhibitors disrupts acute myeloid leukemia (AML) cells' proteostasis, enhancing treatment efficacy and inducing programmed cell death. A novel ...

Autophagy—meaning “self-eating” in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...