Sexual behavior and sex preference in animals and humans are shaped by complex interactions between the brain and hormones during early development. One critical factor is exposure to androgens (male ...

Traditional and new laboratory tools along with advances in AI are outlining a new paradigm in human disease modeling.

Adolescents had significantly higher DLQI scores in the multilinear model compared with adults (β, 3.51; P <.001), meaning that adolescents were associated with a DLQI score increase of 3.51 points.

In an alopecia areata trial, a novel bifunctional therapy that blocks signaling of the interleukin-7 and TSLP pathways produced impressive improvements in hair regrowth during and after therapy.

Patients with severe to very severe alopecia areata saw hair regrowth with bempikibart treatment within 24 weeks. Hair regrowth seemed to persist after treatment cessation to week 36.

References: 1 Passeron T, et al. Baricitinib provides significant hair regrowth in adolescents with severe alopecia areata: 36-week efficacy and safety results from a Phase 3 randomized, controlled ...

Q32 Bio Inc. (Nasdaq: QTTB) ("Q32 Bio"), a clinical stage biotechnology company focused on developing biologic therapeutics to restore immune homeostasis, today announced additional results from ...

Alopecia areata (“AA”) is one of the most prevalent autoimmune diseases in the world, affecting approximately 1 in 1,000 people, with a lifetime incidence of 2% worldwide, or 160 million people.

There were 1317 alopecia areata cases identified in 598,067 children, and almost half of the population was female (49.1%).

Alopecia areata and asthma are strongly linked, particularly through the inflammatory protein IL-33, suggesting a shared biological pathway and potential for targeted treatments like dupilumab.

Alopecia areata may affect up to 2.5% of the United States and global population during their lifetime. 1,2,3 The scalp is the most commonly affected area, but any hair-bearing site can be affected ...

Gilhar A, Schrum AG, Etzioni A, Waldmann H, Paus R. Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies. Autoimmun Rev. (2016) 15:726–35. doi: ...