Circ-EGFR was identified as a novel predictive biomarker for cetuximab efficacy in KRAS wild-type metastatic colorectal ...

Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

Amplified by social media, the overwhelmingly positive balance between population benefit and individual damage is forgotten. This has been the case for Covid vaccinations, where politics and health ...

Selective autophagy ensures the targeted degradation of damaged or surplus cellular components, including organelles, thereby ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Tank-binding kinase 1 (TBK1) is a Ser/Thr ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Paraspeckles are constructed by NEAT1_2 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. ER-phagy, a selective form of autophagic ...

Centrioles are evolutionarily conserved barrels of microtubule triplets that form the core of the centrosome and the base of the cilium. While the crucial role of the proximal region in centriole ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Atherosclerosis is characterized by the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Alternative splicing (AS) leads to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cellular senescence is a form of stable growth ...

Brassinosteroids (BRs) are steroid hormones that are essential for the development of plants. A tight control of BR homeostasis is vital for modulating their impact on growth responses. Although it is ...