Background Anti-C1q autoantibodies can disrupt normal complement function, contributing to the formation of pathogenic immune ...

Background Lupus nephritis (LN) is the most serious complication of SLE. Interstitial fibrosis is the dominant pathological ...

Objective Peer mentoring has been shown to be an effective intervention for chronic conditions with evidence to suggest that ...

Objective Small fibre neuropathy (SFN) is an under-recognised complication of SLE that contributes to chronic pain and ...

Objective To investigate the effects of Qihuang Jianpi Zishen Granules (QJZG) on renal injury in SLE mice, focusing on macrophage M1/M2 polarisation mediated by the AMPK/ULK1 signalling pathway.

Background Social determinants of health (SDoH) contribute to inequities in rheumatic disease care and outcomes especially among individuals with rheumatoid arthritis (RA) and systemic lupus ...

Each year the Lupus Science & Medicine editorial team selects the most meritorious research papers to receive the Lupus Science & Medicine Paper of the Year Award. Primary considerations are the ...

Objective To evaluate the effect of early belimumab administration on disease progression in patients with early active SLE. Methods This multicentre observational study included patients with early ...

Objective To investigate the pharmacokinetics, effectiveness, safety and tolerability of tofacitinib in young adults with active mucocutaneous (MC) SLE manifestations. Methods Patients with SLE and ...