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Panel A shows abnormal expression of major-histocompatibility-complex (MHC) class I antigen on the sarcolemma and sarcoplasm of muscle fibers, with a predilection for perifascicular muscle fibers.
In muscle fibers from lean subjects, the majority of lipid aggregates, from 75 to 90%, were located near the sarcolemma. In muscle fibers from obese subjects, a higher percentage of lipid ...
Curiously, the fungus destroyed the sarcolemma, a kind of sheath around the muscle fibers. But it left intact the neuromuscular junctions, where neurons communicate with the muscles to move them.
It is caused by microruptures in the cell membrane of our muscle fibers. ... Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair. Nature Communications, 2016 ...
Slow twitch muscle fibers support endurance activities like long-distance running, while fast twitch fibers are needed for short, powerful movements such as those involved in heavy weight lifting.
This hinders the muscle fiber's ability to heal, ... interest to patients with Niemann-Pick disease type A since the pre-clinical model for this disease also manifests poor sarcolemma repair." ...