Cytokine networks demonstrate dual functionality. Cytokines are key regulators of immune homeostasis, but paradoxically, cytokines also function as pathogenic drivers in diseases such as systemic ...

A new study found a high prevalence of chronic kidney disease (CKD) among people with systemic lupus erythematosus (SLE), ...

A recent dual-cohort study has found that Lupus Low Disease Activity State (LLDAS) is an attainable and effective treatment target for people with lupus nephritis (LN, lupus-related kidney disease).

Patients with systemic lupus erythematosus with a history of cutaneous lupus erythematosus are more likely to have high ...

Current treatment options for systemic lupus erythematosus (SLE) consists of glucocorticoids, antimalarials, immunosuppressives, and a few biologics, approved or of 'off-label'. Through judicious ...

Discover how targeted therapies are revolutionizing autoimmune disease treatment by offering greater precision.

While hydroxychloroquine (HCQ) helps reduce disease flares in lupus, its effect on renal function in patients with lupus ...

Lupus nephritis articles from across Nature Portfolio Lupus nephritis is an inflammatory kidney disease (glomerulonephritis) that develops in patients with systemic lupus erythematosus (SLE).

Chronic exposure to the systemic inflammation caused by the autoimmune disease may explain the associations found, say the researchers.

Until about 20 years ago, systemic treatment options for moderate/severe psoriasis were limited and nonspecific. To get an idea of how much the field has changed, clinical guidelines on psoriasis ...