What if even a breeze felt like fire, or your leg burned for no reason at all? When pain lingers without a clear cause, that’s neuropathic pain. We are neuroscientists who study how pain circuits in ...

This synaptic noise turns up the brain’s pain sensitivity, both physically and emotionally. It suggests that GluD1 isn’t just managing pain signals, but also may be shaping how those signals feel.

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering ...

Despite its small sample size, this study provides the first direct evidence that acute and chronic pain have different neural representations within the same person’s brain. That evidence underlines ...

A research team has found a small area of the brain in mice that can profoundly control the animals' sense of pain. Somewhat unexpectedly, this brain center turns pain off, not on. It's located in ...

But you do need a brain. No brain - no pain. Don’t believe me? You may not want to accept this – and many can’t at first bite – but it’s a comparatively small step to get there: ...

Neuropathic pain has no immediate cause – research on a brain receptor may help stop this hard-to-treat condition By Pooja Shree Chettiar , Texas A&M University June 23, 2025 ...