Background: Inimmune has developed INI-4001, a novel TLR7/8 agonist as an immunotherapy treatment for cancer. Pre-clinically, the lead formulation of INI-4001 was able to eliminate Lewis Lung ...

The pharma was able to use data from the CLE cohort to back up its premise that selectively blocking the activation of toll-like receptors 7 and 8, which are associated with severe lupus cases ...

Enpatoran shows promising efficacy in lupus rash Merck’s investigational oral TLR7/8 inhibitor significantly improved skin disease activity in patients with cutaneous and systemic lupus erythematosus, ...

Safariland is excited to announce its enhanced collaboration with Axon Enterprise, Inc. in developing the newest suite of holsters and accessories compatible for use with Axon Signal Sensor ...

Safariland’s journey began in 1964, founded on the principle of delivering superior protective equipment to those on the front lines.

Merck tested its oral TLR7/8 inhibitor enpatoran in two forms of lupus. The company reported positive phase 2 data from the cohort of cutaneous lupus erythematosus (CLE) patients late last year.

EIK1001 was initially developed by Seven and Eight Biopharmaceuticals. Eikon licensed global rights to that immunotherapy and another TLR7/8 agonist in 2023; financial terms were not disclosed.

Additionally, Safariland argues that $636,844 of the charges were unrelated to the parts and “clearly improper.” After negotiations, Stellantis reimbursed the supplier $271,988 but has refused ...

What to know: MARA Holdings is lending out 7,377 BTC, about 16% of its total holdings. December bitcoin product fell 2% from November to 890 BTC, still the second-biggest output since April. MARA ...

Mining company MARA, formerly known as Marathon Digital, lent out 7,377 Bitcoin (BTC) to third parties in 2024, according to a Jan. 3 announcement from the Bitcoin miner. Vice president of ...

Deleting the TLR7 gene eliminated the excess interferon response in older male mice and reduced chemically-induced demyelination and associated motor dysfunction in both older males and females.