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People with unresponsive chronic migraine and obesity experienced substantial relief after they started taking a GLP-1 drug, researchers in Italy have found.

From blood sugar to brain relief: GLP-1 therapy linked to lower migraine frequency by European Academy of Neurology edited by Sadie Harley, reviewed by Robert Egan Editors' notes ...

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MR is associated with better treatment response than gepants in patients with migraine who previously had an inadequate response to gepants.

Reference: From blood sugar to brain relief: GLP-1 therapy slashes migraine frequency, Beyond, Meeting: European Academy of Neurology (EAN) Congress 2025.