Shop Lexus RC 350 vehicles in Columbia, SC for sale at Cars.com. Research, compare, and save listings, or contact sellers directly from 247 RC 350 models in Columbia, SC.

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Compare the 2017 Lexus RC 350 and 2017 Lamborghini Huracán. Uncover the best in specs, performance, and innovation for your next ride.

Compare the 2023 Lexus RC 350 and 2023 Lexus LC 500h. Uncover the best in specs, performance, and innovation for your next ride.

Looking for a V8 you can actually live with? The Lexus RC F delivers muscle car thrills with Japanese reliability—making it a ...

The 2026 Lexus LC drops the hybrid model, retaining only the LC500 with a 471-hp V-8 engine. It features a 12.3-inch ...

The RC F Final Edition marks the end of an era for Lexus’ naturally aspirated V8 coupe. Become an AutoGuide insider.

Lexus RC F LMGT3 claims its first-ever WEC win at the 6 Hours of São Paulo, proving it can take on the world’s top endurance racing competitors.

If you're looking for a family-focused luxury SUV that delivers space, tech, comfort, and efficiency, the 2025 Lexus TX 350 ...

Get accurate pricing information for a used 2022 Lexus RC Coupe 2D RC350 F Sport AWD, and explore other options.