Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB ...

Tulane University researchers have developed a new handheld TB test that significantly improves detection in people with HIV, ...

When tested against the traditional IGRA blood test (Interferon-Gamma Release Assay), the ASTRA detected TB in HIV-infected individuals with 87% specificity compared to IGRA's 60%, while also ...

In clinical validation, the ASTRA device outperformed the widely used interferon-gamma release assay (IGRA), which depends on the patient’s CD4+ T cells to produce interferon-gamma (IFNγ).

When tested against the traditional IGRA blood test (Interferon-Gamma Release Assay), the ASTRA detected TB in HIV-infected individuals with 87% specificity compared to IGRA’s 60%, while also ...

Objective: To evaluate the frequency of and factors associated with indeterminate interferon-gamma release assay (IGRA) results in people living with HIV/AIDS (PLWHA). Methods: We tested 81 PLWHA in ...

Interferon-gamma release assays (IGRAs) are now increasingly being used for diagnosis of LTBI, but their role in HCW screening is unclear. A systematic review was conducted of all IGRA studies in HCWs ...

The interferon-gamma release assays (IGRAs) quantifies (in vitro) the cellular immune response of T lymphocytes to specific M. tuberculosis antigens by detecting the interferon-gamma cytokine (IFN-γ) ...

Interferon-gamma release assays (IGRA) are blood tests used to identify people with TB infection. IGRA tests cannot discriminate between latent and active TB. Furthermore, false negatives can occur in ...

Aggarwal, A.N., Agarwal, R., Gupta, D., Dhooria, S. and Behera, D. (2015) Interferon Gamma Release Assays for Diagnosis of Pleural Tuberculosis A Systematic Review ...