During evolution, the innate immune system appeared before the adaptive immune system, and some form of innate immunity probably exists in all multicellular organisms. By contrast with adaptive ...

The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the alarm, mobilizing dendritic cells to fan the flames of inflammation. Antigen-presenting ...

A new study shows how person-to-person variation in antibody immunity plays a key role in shaping which influenza (flu) strains dominate in a population.

Researchers identified a natural 'brake' within the innate immune system: the inhibitory receptor Siglec-E (SigE) and its human counterparts, Siglec-7 and Siglec-9. This receptor helps prevent ...

How chronic activation of the innate immune system can lead to cancer The newer paper, led by first author Hexiao Wang, Ph.D., a postdoctoral fellow in the Petrini Lab, and published in Genes ...

Current treatments to prevent organ transplant rejection focus mainly on suppressing T cells, part of the adaptive immune system. However, the innate immune system—the body's first line of ...

Cells of the innate immune system, such as granulocytes, monocytes (which differentiate into myeloid-derived dendritic cells (DCs) or macrophages) and natural killer (NK) cells, provide an ...

The study shows that these patients have distinct changes in their immune system that link to the severity of their lung damage. This discovery holds promise for developing targeted treatments for ...

The researchers found that longer-lived species had a greater number of genes belonging to the gene families connected to the immune system, suggesting this as a major mechanism driving the ...

Immune cells play fundamental roles in the development, progression, and resolution of both chronic inflammatory diseases and various cancer types. In ...

Its innovative approach aims to harness the innate immune system through three therapeutic approaches: multi-specific NK Cell Engagers via its ANKET ® (Antibody-based NK cell Engager Therapeutics ...