Want to catch a criminal? Show a mugshot on the news. Want to stop HIV infections? Get the immune system to recognize and attack the virus’s tell-tale structure. That’s part of the basic approach ...

The new Science Express study reveals the structure of the CCR5 cell surface receptor, which most strains of HIV use to enter human immune cells. This image shows CCR5 side-by-side with alternate ...

This week, a new paper described how researchers pieced together the entire molecular structure of the protein shell of the HIV virus using GPU-based simulations. This remarkable achievement not ...

A new technique using electron tomography and subtomogram averaging at Diamond's electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host factors.

While finding HIV therapies is a main driver for Yeager's work, he points out that it also provides fundamental insights into biology. "Determining the assembly of a relatively simple structure ...

Scientists have provided the first-ever glimpse of the structure of a key protein -- gp120 -- found on the surface of a specific subgroup of the human immunodeficiency virus, HIV-1. In addition ...

Here, we present the cryo-EM structure, at subnanometer resolution (∼6 Å at 0.143 FSC), of the 'closed', prefusion state of trimeric HIV-1 Env complexed to the broadly neutralizing antibody VRC03.

to show how structure–function relationships of Env proteins can inform the design of an effective HIV-1 vaccine. With special emphasis on the variable regions of gp120, we highlight the ...

Maraviroc thus appears to work against HIV indirectly: not by physically blocking the virus, but by locking the receptor structure into an HIV-insensitive conformation. "Structural details can ...

A new technique using electron tomography and subtomogram averaging at Diamond’s electron Bio-Imaging Centre (eBIC), has solved the structure of the HIV capsid alone and in complex with host ...

Researchers have for the first time unravelled the complex structure of the inner protein shell of HIV. The US team, reporting in Nature, also worked out exactly how all the components of the ...