In Gaucher’s disease, fat accumulates in the cells of organs, often the spleen and liver. There are three types. Type 1, the most common, is not usually fatal but can cause anemia, ...

Gaucher's disease is a rare hereditary illness that impairs the body's ability to break down a type of fat molecule known as glucocerebroside. This disorder is caused by mutations in the GBA gene ...

In Gaucher's disease, this enzyme deficiency causes the fatty substance glucocerebroside to build up inside the macrophages, which then become ineffective and misshapen. At this stage, the cells ...

To the Editor: In discussing the case of a girl with hepatosplenomegaly and pain in the thigh (June 26 issue),1 Larsen arrived at the diagnosis of Gaucher's disease, and he correctly points out th ...

Toward A Less Expensive, More Convenient Treatment Of Gaucher's Disease Date: May 29, 2006 Source: American Chemical Society Summary: Prospects for developing a less expansive and more convenient ...

Gaucher disease can cause symptoms like fatigue, bruises, and bleeding. During your checkups, your doctor will explain how to manage these problems at home. Ask your doctor: ...

Gaucher's disease, also known as glucocerebrosidase deficiency, is an autosomal recessive disease that affects about 1 in 20,000 live births. Type 1, the most common form, does not affect the ...

Dr. Pramod K. Mistry, professor of pediatrics and internal medicine, explains that Gaucher disease does not only affect macrophage cell types. Related diseases such as cancer, Parkinson, and ...

Researchers have implicated a member of the cellular death squad known as the “necrosome” in the pathogenesis of Gaucher’s disease. Receptor-interacting kinase 3 (RIPK3), a protein involved in a type ...