This study presents valuable findings on the patterned loss of Purkinje cells in the mouse cerebellum during aging. Convincing evidence shows that Purkinje cell loss with aging occurs in a pattern of ...

Classification of the cell lines based solely on the observed patterns of gene expression revealed a correspondence to the ostensible origins of the tumours from which the cell lines were derived.

The model then predicts which combination of DNA letters (nucleotide bases: A, T, C, G) are needed for the gene expression patterns required ... and dropped them into mouse blood cells, where ...

Complex traits are influenced by genes and the environment, but especially the latter is difficult to pin down. This important study uses C. elegans to demonstrate that non-genetic differences in gene ...

KDM2A is essential for meiotic initiation and progression by promoting meiotic gene expression and suppressing the expression of genes involved in spermatogonial development. In male germ cells, KDM2A ...

Pxr was shown to be expressed in human, mouse, rat and pig testis, however its roles in the regulation ... associated with a lower expression of some steroidogenic genes. This negative impact of ...

The deviation (in cm) and the accumulation angle (in rad) of the feature pattern in polar expression were extracted to scale the variability at different tremor levels. Then, the proposed intelligent ...

Conclusion We revealed an intimate linkage between HFD-induced microbiota dysbiosis and defect in spermatogenesis with elevated endotoxin, dysregulation of testicular gene expression and ...