The stage is set for the biggest regular season game in NFL history as the Detroit Lions take on the Minnesota Vikings on ...

The Detroit Lions have teased a change for the upcoming Minnesota Vikings game, which is a pivotal game in the season.

The Detroit Lions' game against the 49ers next week might not even matter anymore, or it could end up meaning everything.

It doesn't change the result of last year's NFC Championship, but the Lions' 40-34 win over the 49ers on "Monday Night ...

Here's why the Monday Night Football game between the Detroit Lions and the San Francisco 49ers no longer matters to the ...

The last time the 49ers hosted the Detroit Lions, the stakes could hardly be higher. It was the NFC title game, and the 49ers ...