Corticotropin-releasing factor (CRF) is an early signal of the stress response and is also an important neuromodulator of memory consolidation, anxiety, locomotor activity and food intake. In ...

NBIP-01435 is an investigational long-acting corticotropin-releasing factor type 1 receptor (CRF 1) antagonist. CRF 1 antagonism has been shown to improve androgen control and allow for lower, ...

A new study in Biological Psychiatry reports that overexpression of corticotropin-releasing factor (CRF), a stress-related gene, increases anxious temperament in monkeys. According to Ned Kalin ...

Increased allergic reactions may be tied to the corticotropin-releasing stress hormone ... (SCF) expression, a growth factor of mast cells, in human nasal mucosa- the skin of the nasal cavity.

Neurocrine Biosciences, Inc. (Nasdaq: NBIX) today announced top-line efficacy and safety results from a Phase II clinical trial utilizing Corticotropin Releasing Factor (CRF1) receptor antagonist ...

Roberto et al. Corticotropin Releasing Factor-Induced Amygdala Gamma-Aminobutyric Acid Release Plays a Key Role in Alcohol Dependence. Biological Psychiatry , 2010; DOI: 10.1016/j.biopsych.2009.11.007 ...

Valentino's research focuses on corticotropin-releasing factor (CRF), a hormone released in the brain in responses to stress, in both humans and rats. CRF is a neurotransmitter, meaning it helps ...

Role of corticotropin-releasing factor on bladder function in rats with psychological stress. Share this article Medically reviewed by Madeline Knott, MD — Written by Rachel Ann Tee-Melegrito on ...

Crinecerfont, an oral corticotropin-releasing factor type 1 receptor antagonist, lowered androstenedione levels in phase 2 trials involving patients with CAH. Methods.

To test this idea, they suppressed the activity of the mPFC in some of the mice–and specifically, a group of neurons that produce a hormone called corticotropin-releasing factor (CRF), which is ...