These proteins can have too many conformations for researchers to keep track of, says Kejia Wu, a postdoctoral researcher ...

An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin has ...

Many proteins are capable of spontaneously rearranging themselves within cells to form molecular condensates—membraneless ...

Scientists David Baker's UW lab are using generative AI to target 'undruggable' proteins for creating new drugs and ...

A research team with Professor Neha Kamat used synthetic liposomes and bacterial extracts to generate immune responses ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Small-conductance calcium-activated potassium channel 2 (SK2) serves a variety of biological functions by coupling intracellular calcium dynamics with membrane potential. SK2 modulators are in ...

In a new move, researchers have shown that protein design software can incorporate motion into its outputs. The resulting protein gives a wave with one arm as it binds and releases a calcium ion ...

What if your average researcher could simply ask an AI to design a protein with a single prompt? Last month, researchers gave protein design AI the ChatGPT treatment. From a description of the type, ...

Biophysicists have elucidated why unexpected structures can sometimes arise during protein design. Artificially designed proteins are usually based on building blocks that obey strict rules of ...

Here, we computationally design a calcium-binding switchable peptide–organic hybrid whose conformation and oligomerization state can be controlled by the combined stimuli of light and Ca 2+ binding.

Cradle is one of these, focused on protein design — and it just raised $73 million to build out its labs and team.