Researchers used epigenome engineering and CRISPR to reprogram sperm DNA, allowing embryos to develop with only fathers.

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

They also found that after the extra chromosome was removed, genes tied to nervous system development were more active and ...

Plants face simultaneous abiotic (drought, salinity, heat) and biotic (pathogens, pests) stresses in natural and agricultural ...

CRISPR-Cas systems usually require the guide RNA to match up with a DNA sequence that’s some 18 to 20 genetic letters, or bases, in length. Chances are, Esvelt calculates, ...

CRISPR-Cas systems usually require the guide RNA to match up with a DNA sequence that’s some 18 to 20 genetic letters, or bases, in length. Chances are, Esvelt calculates, there’s no more than one ...

These CRISPR-Cas systems [in nature] are very, very diverse, and we aim to understand this diversity of CRISPR-Cas systems from a fundamental perspective. And also, we hope that, ...

But CRISPR-Cas now appears to go even further than cutting DNA. “When we discovered CRISPR-Cas, we observed that it cuts viral DNA in precise locations,” explains Brouns.

CRISPR-Cas gene editing technology is a groundbreaking method in molecular biology that allows for precise alterations to the genomes of living organisms. This revolutionary technique, ...

CRISPR-Cas will eventually be used for gene therapy – to repair mutated genes that cause disease – but to make it safer, anti-CRISPRs are needed to modulate the technology.

The CRISPR-Cas gene scissors offer a wide range of potential applications, from the treatment of genetic diseases to antiviral therapies and diagnostics. However, to safely harness their powers ...

More information: Edgardo Santiago‐Rivera et al, Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR‐Cas, Angewandte Chemie International Edition (2025). DOI: 10.1002/anie ...