They also found that after the extra chromosome was removed, genes tied to nervous system development were more active and ...

CRISPR-Cas tools allow researchers to modify individual building blocks of genetic material in a precise and targeted manner. Gene therapies based on such gene editing are already being used to ...

Researchers used epigenome engineering and CRISPR to reprogram sperm DNA, allowing embryos to develop with only fathers.

CRISPR-Cas systems usually require the guide RNA to match up with a DNA sequence that’s some 18 to 20 genetic letters, or bases, in length. Chances are, Esvelt calculates, ...

But CRISPR-Cas now appears to go even further than cutting DNA. “When we discovered CRISPR-Cas, we observed that it cuts viral DNA in precise locations,” explains Brouns.

Plants face simultaneous abiotic (drought, salinity, heat) and biotic (pathogens, pests) stresses in natural and agricultural ...

CRISPR-Cas systems usually require the guide RNA to match up with a DNA sequence that’s some 18 to 20 genetic letters, or bases, in length. Chances are, Esvelt calculates, there’s no more than one ...

CRISPR-Cas will eventually be used for gene therapy – to repair mutated genes that cause disease – but to make it safer, anti-CRISPRs are needed to modulate the technology.

These CRISPR-Cas systems [in nature] are very, very diverse, and we aim to understand this diversity of CRISPR-Cas systems from a fundamental perspective. And also, we hope that, ...

More information: Edgardo Santiago‐Rivera et al, Spider Eye Development Editing and Silk Fiber Engineering Using CRISPR‐Cas, Angewandte Chemie International Edition (2025). DOI: 10.1002/anie ...

CRISPR-Cas gene editing technology is a groundbreaking method in molecular biology that allows for precise alterations to the genomes of living organisms. This revolutionary technique, ...

This insight reveals how to tune Cas removal, contributing to future CRISPR applications. "Polarity of the CRISPR Roadblock to Transcription" published Dec. 5 in Nature Structural & Molecular Biology.