Public health experts are concerned that misuse and overuse of antibiotics during the pandemic could exacerbate another ongoing crisis: antibiotic resistance, where pathogens like bacteria and ...

Three clinical trials have examined the efficacy and safety of single dose azithromycin (30 mg/kg) in children with uncomplicated acute otitis media (AOM). In the first trial, a small pilot study ...

The 20-mg/kg/day dose of azithromycin for 3 days may also be better than the 10-mg/kg/day dose for 3 days in terms of minimizing the risk of emerging resistance in the GABHS. [35,43] Using the ...

GSK has reported topline results from a phase 3 trial of its novel antibiotic gepotidacin that could spell the end of a decades-long drought in new oral therapies for gonorrhoea. In the EAGLE-1 ...

AbbVie has claimed FDA approval for Emblaveo, a new antibiotic product to treat complicated intra-abdominal infections (cIAI), including those caused by Gram-negative bacteria that represent a ...

When a medication works right, it boosts your health or helps you feel better. But a drug can bring on problems if it doesn't mix well with something else you put into your body, like another ...

Here, Li et al. show that constitutive hydrolysis of ATP and NADH (or ‘bioenergetic stress’) potentiates the evolution of antibiotic resistance and persistence in E. coli.