GLP-1 receptor agonist indications continue to expand beyond glycaemic and weight control, with benefits now shown in chronic kidney disease in type 2 diabetes, obesity-related heart failure, knee ...

Physical activity programmes such as the NSC can help mitigate rising obesity and T2DM prevalence when implemented at the population level, as seen in Singapore. However, their success depends on ...

We present one of the first comprehensive evaluations of predictive information derived from retinal fundus photographs, illustrating the potential and limitations of readily accessible and low-cost ...

Each year, millions of individuals are admitted to intensive care units (ICUs) worldwide; for every patient treated in the ICU, there is often at least one other unseen vulnerable individual—the ...

As the global population ages, older adults with atherosclerotic cardiovascular disease (ASCVD) are projected to drive a ...

Venous thromboembolism includes deep vein thrombosis (DVT) and pulmonary embolism, which have incidence rates of between 1 and 2 cases per 1000 people for the first episode.1,2 Strong, provoking risk ...

Men and partners are important contributors to the health of future generations, yet their own preconception health and wellbeing remain secondary considerations in research, practice, and policy.

Neuropathological confirmation of Alzheimer's disease is defined by the presence of extracellular amyloid-β plaques and intracellular neurofibrillary tau tangles. A central challenge to the ...

The DIRECT ANGIO randomised clinical trial by Benjamin Gory and colleagues1 in The Lancet Neurology was designed to test a biologically compelling premise: that a direct transfer to angiography suite ...

Chronic hepatitis D coinfection affects an estimated 12 million people globally, with higher prevalence in low-income and middle-income countries, especially the African and Western Pacific regions.

There was some evidence that cannabinoids can reduce symptoms of cannabis use disorder, insomnia, tic or Tourette's syndrome, and autism spectrum disorder, but the quality of this evidence was ...

As the inaugural Director of the new Parkinson's Research Centre, funded by the UK Dementia Research Institute and Parkinson's UK, Professor Miratul Muqit (University of Dundee, UK) hopes to untangle ...