Background Intercurrent infections are presumed potential triggers of systemic lupus erythematosus (SLE) disease flares. 1 However, most of the evidence is obtained from a limited number of ...

Background Pregnant women with antiphospholipid antibodies and/or lupus have higher rates of adverse pregnancy outcomes (APOs), such as fetal loss and preterm birth due to severe preeclampsia (PE) or ...

Background Discoid lupus erythematosus (DLE) is one of the LE-specific skin diseases on the scalp, and some cases induce scarring alopecia. In systemic LE (SLE), variable nail changes not specific to ...

Background Lupus nephritis (LN) is a common manifestation of systemic lupus erythematosus (SLE), with 10–30% progressing to end-stage renal disease (ESRD) and requiring dialysis. Kidney ...

Background We employed urine proteomics to define the molecular signatures associated with the histological features quantified by the NIH activity and chronicity indices. Methods We employed urine ...

Description Chilblain lupus erythematosus(CHLE) or Perniosis is a rare and chronic form of lupus involving the toes, fingers, nose, and ears precipitated by cold ...

Background Chronic and latent infections like tuberculosis (TB) are known triggers for developing autoimmunity. It is not known the consequences of latent TB infection (LTBI) in individuals who are ...

Background Very limited and old data regarding the epidemiology of juvenile-onset SLE (jSLE) are available. Our aim was to estimate jSLE incidence and mortality rate in incident cases over the period ...

Description Myocarditis is a rare presentation of systemic lupus erythematosus (SLE) and its diagnosis can be challenging as its non-specific clinical presentation varies greatly from being ...

Background Often, patients present with clinical symptoms and immunologic abnormalities suggestive of systemic lupus erythematosus(SLE), while not meeting classification criteria yet. This is referred ...

Background Mutations, both activating and inactivating ones, continue to be identified in human diseases, including systemic lupus erythematosus (SLE). One emphasis is on mutations in transcription ...

Background Although the safety profile of COVID-19 vaccines was shown to be acceptable in the clinical trials, risk and benefit of the vaccines in patients with systemic lupus erythematosus (SLE) are ...