Who are the 10 greatest San Francisco 49ers of all time? FOX Sports Research compiled the list of Niner greats.

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

The Detroit Lions and the San Francisco 49ers will go head to head for Monday Night Football this week, but tight end George Kittle is kicking things off with nothing but love, at least as it relates ...

Judges declare the 2020 conviction of the former NFL Defensive Player of the Year is ‘legally invalid’ after finding his race ...

The 49ers just lost 29-17 to the Miami Dolphins. Here are the 49ers' grades for this performance. QUARTERBACK: C Brock Purdy ...

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

Tua Tagovailoa threw for 215 yards and a touchdown, Jason Sanders nailed five field goals, and the Miami Dolphins kept their ...

Winters (chest) was a full participant in Thursday's practice. Winters picked up a chest issue in Sunday's loss to Miami, but his ability to practice in full Thursday suggests that he's not ...

The 49ers have made a couple of roster moves, while also shutting down a defensive player for the season’s final two games. San Francisco announced left tackle Trent Williams has been placed on ...