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So University of Utah biologists, led by assistant professor Jamie Gagnon, tackled the problem by comparing two fish species: zebrafish, which can regenerate its heart, and medaka, which cannot.
the researchers deleted five key enhancers in zebrafish. The result was a significant impairment in both the development of sensory cells during embryonic stages and their regeneration after damage.
This subpopulation that the researchers described as a transient regeneration-activated cell state (TRACS) showed gene enrichment for ECM modifiers and embryonic morphogenesis ... who investigates ...
Green fluorescent proteins show where bone-building is occurring in the regeneration of a zebrafish caudal fin that had been amputated. Complete repairs begin at the tail's base and gradually ...
Though the salamander is a stalwart regeneration model, research is expanding into model organisms such as the zebrafish and mouse, which offer broader tools and possibly better translation to ...
Weekly breeding ensures the embryo supply. So far zebrafish studies have yielded insights into cancer, diabetes, muscle diseases, and more. Elizabeth Burke, a researcher at the National Institutes ...