The return of Patrick Dempsey to network television sees him play a character whose difficult story is crueler than Derek's ...

Kathleen Shepherd is played by Amy Acker on the Grey's Anatomy cast. Her first episode is Season 15, episode 21 as Derek Shepherd's sister.

Dr. Derek Shepherd, MD, played by actor Patrick Dempsey, was a mainstay on Grey’s Anatomy. Often referred to as “McDreamy” by fans of the ABC medical drama, Shepherd was killed off in the TV ...

Dr. Derek Shepherd is remembered as being "Dr. McDreamy," but these moments in his relationship with Meredith show cracks in that image.

In arguably his most beloved and well-known role, this year’s Sexiest Man Alive played Dr. Derek Shepherd on Grey’s Anatomy for 11 seasons before his character’s heartbreaking death.

Derek Shepherd's Fourth Sister, Kate, Is Joining Grey's Anatomy — Here's Who's Playing Her! By Quinn Keaney Updated on Feb 21, 2019 at 3:50 PM Getty | John Lamparski ...

With Derek Shepherd's (Patrick Dempsey) elusive fourth sister finally headed toGrey's Anatomy, we now know who is set to play her. The Gifted star Amy Acker will take on the role of Kathleen ...

Grey's Anatomy has cast Derek Shepherd's fourth sister, who will be seen on screen for the first time this season. The Hollywood Reporter says that the casting is a "one-off", suggesting that ...

Why Patrick Dempsey cried when he returned to play Derek Shepherd in 'Grey's Anatomy' Season 17 alongside Ellen Pompeo (Meredith Grey).

Patrick Dempsey, who played Derek Shepherd, left "Grey's Anatomy" in season 11 but has been back during the latest season as a guest star.

"I'll be back before you know it," said hunky Dr. Derek Shepherd, flashing a smile as he walked away from wife Meredith Grey at the start of Thursday's Grey's Anatomy episode. But now we know: He ...

EW confirmed on Friday that Grey's Anatomy is currently on the hunt for an actress to play Kathleen, who is the fourth sister of the late Derek Shepherd (Patrick Dempsey).