In conclusion, the mutant strains of the YMDD motif of HBV polymerase could be ... the rapid selection of resistant strains. The wild type virus was inhibited by lamivudine selection pressure ...

MEME-ChIP performs two complementary types of de novo motif discovery: weight matrix–based discovery for high accuracy; and word-based discovery for high sensitivity. Motif enrichment analysis ...

Part of the HBV polymerase gene flanking the YMDD motif was sequenced after polymerase ... selected at random from each sample and YMDD wild type and mutant strains were detected by real-time ...