For example, some genetic changes consist of rearrangements and more ... or may be completely unable to do its job. A specific type of gene mutation, such as BRCA2 mutations, may raise the ...

Mayo Clinic researchers have identified a potential new way to monitor the progression of high-grade gliomas, one of the most ...

The addiction of cancer cells to causal gene fusions often results in amplification, in vivo, which can be exploited to reveal unidentified recurrent gene rearrangements ... which are made up of ...

CML is caused by a rearrangement of genetic material between two chromosomes ... polymerase chain reaction (RT-PCR) test, a type of blood test, to measure a patient's response to CML treatment.

In balanced structural changes, the genetic material ... cells generally gain multiple types of chromosomal aberrations during tumor progression, including rearrangements, deletions, and duplications.

80% of infants with acute lymphoblastic leukemia have a genetic rearrangement of the KMT2A gene. About 40% of infants with ...

Many types of mutations can be introduced into a model gene in this way, including null or point mutations and complex chromosomal rearrangements such as large deletions, translocations ...

Scientists report adaptive divergence in cryptic color pattern is underlain by two distinct, complex chromosomal rearrangements, where millions of bases of DNA were flipped backwards and moved from ...

The PedAL (Pediatric Acute Leukemia) Master Trial is at the heart of LLS's Dare to Dream Project to transform treatment and care for kids with blood cancer Infants and children with specific types ...

Researchers have explored the evolution of the genetic change that causes chronic myeloid leukaemia and show its ability to drive the disease.