Many types of mutations can be introduced into a model gene in this way, including null or point mutations and complex chromosomal rearrangements such as large deletions, translocations ...

The Leukemia & Lymphoma Society (LLS) announced today the first pediatric patient has received treatment in a new subtrial of ...

In balanced structural changes, the genetic material ... cells generally gain multiple types of chromosomal aberrations during tumor progression, including rearrangements, deletions, and duplications.

Scientists report adaptive divergence in cryptic color pattern is underlain by two distinct, complex chromosomal rearrangements, where millions of bases of DNA were flipped backwards and moved from ...

The addiction of cancer cells to causal gene fusions often results in amplification, in vivo, which can be exploited to reveal unidentified recurrent gene rearrangements ... which are made up of ...

A new study has unveiled when chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow, arises in ...

A new study shows that Arima Genomics’ technology detects actionable cancer drivers in solid tumors missed by FISH, RNA, and DNA sequencing tests.

Chromosomal rearrangements where large chunks of chromosomes are inverted, moved, deleted or duplicated, provide a possible source for such large-scale "macromutations." However, characterizing ...

Baylor College of Medicine offers preimplantation genetic ... main types of PGT. Examples of conditions that PGT can test for include: Chromosome conditions (aneuploidy), such as Down syndrome, ...

A new study has unveiled when chronic myeloid leukemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

enabling more accurate detection of complicated genetic changes, authors describe a complex rearrangement that resulted in the inactivation of the RFX3 gene. The resulting clinical diagnosis of ...